If you disabled support for old TLS 1.0 version and you are only supporting TLS 1.2 you may end up having some problems within your environment. This is normally disabled because of the new PCI/DSS requirements.
The below is a list of common issues and what to do to fix it.
To fix Remote Desktop Connection install the following: (Windows 7 Users Only)
Users will not be able to connect to remote servers.
To fix SQL Management Studio connection use the following: (Any Windows)
Users will not be able to use SQL Management Studio to connect to databases
Install .Net 4.6 or 4.6.1
To fix local IIS copies. use one of the following depending on .Net version and Windows version.
Users will not be able to run local copies under IIS. Storefront error will appear on the local site.
You need to update one of the .Net version depending on which version your local site is running.
ADO.NET – SqlClient (.NET Framework 4.5.2, 4.5.1, 4.5)
ADO.NET – SqlClient (.NET Framework 4.0)
ADO.NET – SqlClient (.NET Framework 3.5/.NET Framework 2.0 SP2)
and also other updated you may need installing to fix other problems.
and also Microsoft Tutorial